“BLACK SEED- MEDICINE FOR ALL DISEASES EXCEPT DEATH " (Sahih Bukhari)   SCIENTIFIC CLASSIFICATION  Nigella sativa  is division from Magnoliophyta, order Ranunculales, family Ranunculaceae, genus Nigella and species N.sativa.   Scientific Classification   Kingdom  : Plantae Division : Magnoliophyta Order  : Ranunculales Family  : Ranunculaceae Genus : Nigella Species : N.sativa    In botany it is called Nigella sativa.     CHEMICAL COMPOSITION     Black Seed contains 1.5% fizz oil, while 37.5% non fizz oil. Besides that, also found albumen, sugar, organic acid, and glycoside melanthin metarbin.   OIL COMPOSITION   Black Seed contains high fatty acids that very important for optimal health of the body. The acids can't be process (non-synthesis) by body in sufficient number, so its presence in the black seed is very beneficial if taken to help the body get health resources.   Medical preparations containing linoleic and linolenic acids has been widely used for the treatment to lower blood cholesterol, eczema and skin diseases, pre-menstrual stress, a variety of tumors, blood clotting disease (arterio-thrombotic diseases), rheumatoid arthritis and sclerosis.     VOLATILE OIL ANALYSIS   Analysis of the content volatile oil (essential oil) in the black seed shows the content of the ingredients have been proven to provide the following response. Seed, which contains one of four volatile oil has the following composition  :-    Volatile Oil Result Analysis   Volatile Oil Percents (%) Characteristic Cymene 32 % Used because of its ability to act in cases of rheumatism pain Pinene 3 % If ingested can add some expectorant and colic effect. If used externally as it affects Cymene. Carbony 25 % Having the ability to be antiseptic and antibiological. From further tests it was confirmed effective against gram-positive and gram-negative organisms. Carvone 0.05 % Known to have anti-colic and flatulence. Limonene 27 % Effective in the treatment gallstone. Nigellon semohiprepinon 1.5 % When rubbed on the chest or smell it to expand the respiratory tract, absorbing the pain caused by the natural muscular contractions (cramps ~ painful involuntary muscular contraction), increasing its temperature, thus reducing the effects of bronchial asthma and cough. It also inhibits production of histamine. Thymochinon   It prevent infection, pain, stimulates the gall bladder and acts as an anti-oxidant   BIOCHEMICAL CONTENT     In simple table, the following are biochemical content:-   Alanine Arginine Acid ascorbic Asparagines Campesterol Carvone Cymene Cystine Acid dehidroaskorbic Thimohidroquinone Alpha spinasterol Acid eicosadienoic Glucose Acid Glutamic Glicine Iron Isoleucine Leucine D-limonene Lipase Acid linoleic Acid linolenic Lysine Methionine Acid miristic Nigellin Acid oleic Acid palmitic Phenylalanine Phitosterols Potassium Beta-sitosterol Acid stearic Alpha spinasterol Stigmasterol Tannin Threonine Thimohidroquinone Thimoquinone Triptophan   CHARACTERISTIC PHARMACOLOGY AND TOXICOLOGY BLACK SEED   Pharmacology reaction from black seed extract (as part of its active components such as volatile oil and thimoquinone) reported to provide a protective effect against nephrotoxicity (toxic effects on the kidney complications) and hepatotoxicity (toxic effects on the liver complications) due to either illness or chemical sources. Seed and oil has activities such as anti-inflammatory, analgesic, antipyretic, antimicrobial and antineoplastic. Oil to reduce high blood pressure and improve breathing. Treatment of mice with extracts of black seed for 12 weeks have made change haemogram result that include the addition of packed cell volume (PCV) and haeglobin (Hb) and a decrease in plasma concentrations of cholesterol, triglycerides and glucose. Seed deemed to be very low in toxic. Observations on the extract and the oil has shown it has no negative effects on the liver and kidneys. However, useful effects in the use of seeds and thymoquinone is that it has the ability as an antioxidant and cytoprotective, its impact on some cause inflammation.

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